2-[(Tetrahydro-2H-pyran-4-ylcarbonyl)amino]-acetic acid - Names and Identifiers
2-[(Tetrahydro-2H-pyran-4-ylcarbonyl)amino]-acetic acid - Physico-chemical Properties
Molecular Formula | C8H13NO4
|
Molar Mass | 187.19 |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD11169983 |
2-[(Tetrahydro-2H-pyran-4-ylcarbonyl)amino]-acetic acid - Risk and Safety
2-[(Tetrahydro-2H-pyran-4-ylcarbonyl)amino]-acetic acid - Introduction
2-[(Tetrahydro-2H-pyran-4-ylcarbonyl)amino]-acetic acid, also known as THPPCAA, is a compound whose chemical formula is C9H15NO4. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
1. Appearance: THPPCAA is solid, common is powder white crystal.
2. solubility: soluble in water, and poor solubility in organic solvents such as alcohol and ether.
3. Melting point: The melting point of the compound is in the range of 130-132°C.
4. Chemical properties: THPPCAA is an organic compound with amide structure, which can be synthesized by the reaction of carboxylic acid and amine.
Use:
1. Pharmaceutical field: THPPCAA is an important intermediate, which is often used in the synthesis of drugs in the field of medicine, especially for the synthesis of biologically active molecules and drug candidate compounds.
2. Chemical research: THPPCAA is also widely used in organic synthesis research, for the construction of compound skeleton and synthesis of crosslinkable polymers.
Preparation Method:
THPPCAA can be prepared by the following synthetic route:
1. First, 2,5-dihydroxyethyl -2,5-diethyl -2,5-dihydrofuran (THF) is oxidized to obtain the corresponding carboxylic acid.
2. Next, the carboxylic acid is reacted with amines to produce the target compound THPPCAA.
Safety Information:
There is currently no specific information on the safety information of the THPPCAA. However, in general, for the use of any chemical substances, strict compliance with safe operating procedures should be observed, including wearing appropriate personal protective equipment, avoiding direct contact with skin and eyes, avoiding inhalation of dust or vapor, and ensuring that it is in a well-ventilated environment Operate and stay away from open flames and ignited substances. If necessary, it is recommended that the compound be used and handled under the guidance of a professional.
Last Update:2024-04-09 21:54:55